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Humanin is a mitochondrial-derived peptide (MDP) known for its potent cytoprotective properties. Supplied as a 10mg lyophilized peptide, this reagent is engineered for high-purity laboratory applications, providing the structural consistency required for advanced studies in cell survival pathways, mitochondrial homeostasis, and the suppression of apoptosis in various cellular models.

Peptide Profile

• Sequence: Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala

• Molecular Formula: $C_{119}H_{204}N_{34}O_{32}S_{2}$

• Molecular Weight: 2687.2 g/mol

• Appearance: Lyophilized white powder

Laboratory Utility

• Cytoprotective Research: Utilized as a standardized reference in studies exploring the role of Humanin in preventing cell death induced by diverse stressors, including oxidative damage and amyloid-beta toxicity.

• Mitochondrial Signaling: Serves as a primary reference peptide for investigating mitochondrial-nuclear communication and the metabolic regulation of cell survival.

• Analytical Benchmarking: Provides a consistent reference material for building analytical databases for peptide mapping, HPLC, and mass spectrometry verification in cell biology research.

Laboratory Protocols

Storage: Store lyophilized peptide at -20°C in a desiccated environment. Once reconstituted with sterile diluent, store at 4°C for immediate use or aliquot and store at -80°C to prevent degradation from repeated freeze-thaw cycles.

Safety: Strictly for in vitro laboratory research. Requires standard sterile technique and appropriate PPE (gloves, goggles) for bench-level handling in a controlled laboratory environment.

Key Specifications