Enclomiphene

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* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.

Buy Enclomiphene Online 

Buy Enclomiphene online in usa at the premier provider for buy high-quality research chemical compounds online usa since 2009, MyChems simplifies procurement for laboratories mapping out how to buy research chemicals safely. Our catalog features a comprehensive range of substances, including Benzodiazepines usa and Lysergamides usa, as well as Tryptamines usa, peptides usa, and SARMs usa, ensuring that research facilities have reliable access to the materials necessary for their specific projects. research chemicals for sale usa. Enclomiphene is the (E)-isomer of clomiphene, a selective estrogen receptor modulator (SERM). Unlike the mixed-isomer clomiphene citrate, Enclomiphene acts as a more specific antagonist at estrogen receptors in the hypothalamus and pituitary gland. This reagent is engineered for high-purity laboratory applications, providing the consistency required for advanced studies in gonadotropin secretion, endocrine feedback regulation, and testosterone biosynthesis pathways in in vitro models.

Compound Profile

  • Chemical Name: (E)-2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanamine

  • Molecular Formula: $C_{26}H_{28}ClNO$

  • Molecular Weight: 405.96 g/mol

  • Appearance: White to off-white crystalline powder

  • Purity: $>99\%$ (HPLC analyzed)

Laboratory Utility

  • Endocrine Feedback Research: Utilized as a standardized reference in studies exploring the blockade of estrogen-mediated negative feedback at the pituitary and hypothalamic level.

  • Gonadotropin Signaling: Serves as a primary reference compound for investigating the resulting increase in endogenous luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion in cellular models.

  • Analytical Benchmarking: Provides a highly consistent reference material for validating HPLC separation protocols, mass spectrometry verification, and building analytical databases for SERM research.

Laboratory Protocols

Storage: Store in a cool, dry, dark environment (e.g., -20°C or 4°C in a desiccator) to maintain long-term structural integrity. Keep the container tightly sealed and protected from light and moisture.

Safety: Strictly for in vitro laboratory research. Requires standard chemical handling procedures, including the use of appropriate personal protective equipment (PPE) such as gloves, a lab coat, and safety goggles. Perform all operations in a well-ventilated laboratory environment.

Key Specifications

Parameter Specification / Details
Primary Compound Name Enclomiphene Citrate (Non-Steroidal SERM)
CAS Registry Number 15690-28-5 (Base), 7599-79-3 (Citrate)
IUPAC Designation 2-[4-[(Z)-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid
Synonyms / Trade Names Androxal, Enclomifene
PubChem CID 9880068 (Citrate)
Molecular Formula C35​H36​ClNO9​ (Citrate Salt)
Molar Mass / Weight 598.1 g/mol
Physical Appearance White to pale yellow crystalline powder (raw) / Clear or slightly tinted liquid (suspended)
Solubility Profile Soluble in DMSO, Methanol, and Ethanol. Slightly soluble to insoluble in water.
Tested Purity ≥98% via HPLC
Active Ingredient (Total) 375mg per 30mL vial
Dry / Powder Formulations N/A (Liquid suspension)
Liquid / Solution Concentrations 12.5mg/mL in a PEG 400 / Ethanol carrier
Alternative Formulations Clomiphene Citrate (the mixed-isomer parent compound), Tamoxifen
Storage Guidelines Store at room temperature (20°C to 25°C). Protect strictly from moisture, heat, and direct sunlight.
Estimated Shelf Life 24 months from manufacture date.
Safety Documentation Standard SDS available for Enclomiphene Citrate
Terms of Application For laboratory research purposes only. Not for human or veterinary use. Investigated for its highly selective non-steroidal estrogen receptor antagonism, specifically evaluating its ability to block negative feedback loops at the hypothalamic-pituitary axis and stimulate endogenous gonadotropin (LH/FSH) release in cellular models.

Foundational Scientific Overview

Enclomiphene Citrate is a prominent subject within the field of selective estrogen receptor modulators (SERMs). Originally synthesized to investigate the modulation of antagonizing estrogen receptors, it has become a staple for researchers examining endocrinology and reproductive biology research. This compound is commonly supplied in enclomiphene liquid and tablet formats for controlled laboratory studies.

At 4 Amino Lab, we provide this compound in tablet and liquid solution to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity. Our enclomiphene tablets and liquid formats are frequently cited in peer-reviewed literature due to their well-documented interaction with Hypogonadal signaling pathways.

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