AOD-9604 (5mg)
$45.00
* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.
Key Specifications
| Category | Parameter | Specification / Details |
|---|---|---|
| Identification & Nomenclature | Primary Compound Name | AOD-9604 (HGH Fragment 177-191) |
| CAS Registry Number | 221231-10-3 | |
| Sequence / IUPAC | Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe | |
| Chemical & Physical Properties | Molecular Formula | C78H123N23O23S2 |
| Molar Mass / Weight | 1815.1 g/mol | |
| Physical Appearance | White lyophilized (freeze-dried) solid/powder | |
| Solubility Profile | Highly soluble in Bacteriostatic Water and sterile water. | |
| Product Specifications | Tested Purity | ≥98% via HPLC |
| Active Ingredient (Total) | 5mg per vial | |
| Dry / Powder Formulations | Lyophilized powder | |
| Handling & Logistics | Storage Guidelines | Lyophilized: Store at -20°C for long-term stability. Protect from light.Reconstituted: Must be refrigerated at 2°C to 8°C. |
| Estimated Shelf Life | 24 months from manufacture date (lyophilized). | |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. Investigated as a C-terminal peptide fragment of hGH to evaluate beta-3 adrenergic receptor modulation and targeted lipolysis in in-vitro adipocyte assays, specifically without inducing IGF-1 or altering glucose homeostasis. |
Foundational Scientific Overview
AOD-9604 (5mg) is a highly specialized subject within the field of localized lipolysis and beta-adrenergic receptor modulation. Synthesized as a modified C-terminal fragment of human Growth Hormone (tyrosine-hGH 177-191), it has become a staple for researchers examining fat catabolism without the associated anabolism, IGF-1 elevation, or insulin resistance typical of full-length GH.
At 4 Amino Labs, we provide this highly purified peptide fragment to ensure experimental reproducibility across varied lipid metabolic assays.
Scientific Literature Reference: The biochemical isolation of the lipolytic domain of human growth hormone, proving its capacity to upregulate fat oxidation independently of the growth hormone receptor, is a cornerstone of lipolytic research. See: Heffernan, M. A., et al. (2001). “The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice.” Endocrinology, 142(12), 5182-5189.
Analytical Composition & Purity Standards
- Chemical Formula: C78H123N23O23S2
- Physical State: White Lyophilized Solid
Our AOD-9604 undergoes a multifaceted verification process via independent High-Performance Liquid Chromatography (HPLC) to ensure a purity threshold of ≧ 99%, guaranteeing the absence of elongated or functionally altered sequences.
Investigational Pathways
Researchers utilizing AOD-9604 typically focus on the following biochemical mechanisms:
- Beta-3 Adrenergic Sensitization: Evaluating the compound’s capacity to upregulate $\beta_3$-AR expression in isolated pre-adipocyte models.
- Hormone-Sensitive Lipase (HSL) Activation: Observing the direct triggering of triglyceride hydrolysis without cAMP elevation.
- Lipogenesis Inhibition: Mapping the compound’s capacity to halt the conversion of glucose and free fatty acids into stored lipids.
- Chondrogenic Repair: Investigating secondary applications regarding the upregulation of proteoglycan and collagen synthesis in joint tissue assays.
Laboratory Handling & Stability Protocol
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of AOD-9604, the following storage parameters are recommended:
- Thermal Regulation: Store in a strictly controlled, refrigerated, and desiccated environment.
- Photostability: Protect from direct UV exposure; storage in an opaque container is advised.
- Contamination Control: Utilize sterilized instruments and work within a laminar flow hood where possible.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
Frequently asked questions
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A seemingly elegant design can quickly begin to bloat with unexpected content or break under the weight of actual activity. Fake data can ensure a nice looking layout but it doesn’t reflect what a living, breathing application must endure. Real data does.
Websites in professional use templating systems. Commercial publishing platforms and content management systems ensure that you can show different text, different data using the same template. When it’s about controlling hundreds of articles, product pages for web shops.
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