LGD-4033 (Ligandrol)
$52.00
* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.
Key Specifications
| Parameter | Specification / Details |
|---|---|
| Primary Compound Name | LGD-4033 (Selective Androgen Receptor Modulator) |
| CAS Registry Number | 1165910-22-4 |
| IUPAC Designation | 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile |
| Synonyms / Trade Names | Ligandrol, VK5211 |
| PubChem CID | 44137686 |
| Molecular Formula | C14H12F6N2O |
| Molar Mass / Weight | 338.25 g/mol |
| Physical Appearance | White to off-white crystalline powder (raw) / Clear or slightly tinted liquid (suspended) |
| Solubility Profile | Soluble in DMSO, Ethanol, and Propylene Glycol/PEG 400. Insoluble in water. |
| Tested Purity | ≥99% via HPLC |
| Active Ingredient (Total) | 300mg per 30mL vial |
| Dry / Powder Formulations | N/A (Liquid suspension) |
| Liquid / Solution Concentrations | 10mg/mL in a PEG 400 / Ethanol carrier |
| Alternative Formulations | LGD-3303 (a closely related but structurally distinct SARM) |
| Storage Guidelines | Store at room temperature (20°C to 25°C). Protect strictly from moisture, heat, and direct sunlight. |
| Estimated Shelf Life | 24 months from manufacture date. |
| Safety Documentation | Standard SDS available for LGD-4033 |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. Investigated for its high-affinity, tissue-selective binding to the androgen receptor to evaluate anabolic signaling pathways in musculoskeletal in-vitro models. |
Foundational Scientific Overview
LGD-4033 (Ligandrol) is a prominent subject within the field of musculoskeletal research and targeted anabolism. Synthesized as a highly potent, non-steroidal Selective Androgen Receptor Modulator (SARM), it serves researchers examining the tissue-selective binding of the androgen receptor (AR) designed to mimic the anabolic effects of testosterone in muscle and bone without the associated androgenic hypertrophy in prostate or sebaceous tissues.
At 4 Amino Labs, we provide this compound in a highly pure format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.
Scientific Literature Reference: The biochemical capacity of novel non-steroidal ligands to induce profound anabolic activity while sparing secondary organs from androgenic side effects is heavily documented. See: Basaria, S., et al. (2013). “The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men.” The Journals of Gerontology: Series A, 68(1), 87-95.
Analytical Composition & Purity Standards
- Chemical Formula: C14H12F6N2O
- Physical State: Fine Crystalline Solid
Our LGD-4033 undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≥ 99%. This analytical rigor ensures the absolute absence of steroidal contaminants.
Investigational Pathways
Researchers utilizing LGD-4033 typically focus on the following biochemical mechanisms:
- Selective AR Agonism: Evaluating the compound’s high-affinity binding kinetics at the androgen receptor within isolated myocyte cultures.
- Protein Synthesis: Observing the downstream transcriptional activation of myogenic regulatory factors leading to cellular hypertrophy.
- Osteoanabolic Activity: Mapping the flux of bone mineral density markers and osteoblast proliferation in musculoskeletal assays.
- Tissue Sparing Models: Investigating the minimal transcriptional activity in isolated prostate cellular models compared to standard steroidal controls.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of LGD-4033, the following storage parameters are recommended:
- Thermal Regulation: Store in a strictly controlled, desiccated environment at room temperature.
- Photostability: Protect from direct UV exposure; storage in an opaque container or dark cabinet is advised to prevent photodegradation.
- Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
Frequently asked questions
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A seemingly elegant design can quickly begin to bloat with unexpected content or break under the weight of actual activity. Fake data can ensure a nice looking layout but it doesn’t reflect what a living, breathing application must endure. Real data does.
Websites in professional use templating systems. Commercial publishing platforms and content management systems ensure that you can show different text, different data using the same template. When it’s about controlling hundreds of articles, product pages for web shops.
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