MOTS-c (10mg)
$50.00
* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.
Key Specifications
| Category | Parameter | Specification / Details |
|---|---|---|
| Identification & Nomenclature | Primary Compound Name | MOTS-c (Mitochondrial Derived Peptide) |
| CAS Registry Number | 1627580-64-6 | |
| Sequence / IUPAC | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg | |
| Chemical & Physical Properties | Molecular Formula | C101H152N28O22S2 |
| Molar Mass / Weight | 2174.6 g/mol | |
| Physical Appearance | White lyophilized (freeze-dried) solid/powder | |
| Solubility Profile | Highly soluble in Bacteriostatic Water and sterile water. | |
| Product Specifications | Tested Purity | ≥98% via HPLC |
| Active Ingredient (Total) | 10mg per vial | |
| Dry / Powder Formulations | Lyophilized powder | |
| Handling & Logistics | Storage Guidelines | Lyophilized: Store at -20°C for long-term stability. Protect from light.Reconstituted: Must be refrigerated at 2°C to 8°C. |
| Estimated Shelf Life | 24 months from manufacture date (lyophilized). | |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. Investigated as a mitochondrial-derived peptide evaluating AMPK activation, mitochondrial metabolic regulation, and skeletal muscle glucose homeostasis in cellular models. |
Foundational Scientific Overview
MOTS-c (10mg) is a paramount subject within the field of mitochondrial bioenergetics and cellular metabolic homeostasis. Synthesized as a mitochondrial-derived peptide (MDP), it serves researchers examining the activation of the AMP-activated protein kinase (AMPK) pathway, glucose uptake modeling, and the prevention of diet-induced metabolic dysfunction in-vitro.
At 4 Amino Labs, we provide this highly sensitive sequence in a stabilized lyophilized format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.
Scientific Literature Reference: The biochemical capacity of MOTS-c to act as a systemic metabolic regulator, targeting skeletal muscle to enhance insulin sensitivity and beta-oxidation, is a cornerstone of recent mitochondrial research. See: Lee, C., et al. (2015). “The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.” Cell Metabolism, 21(3), 443-454.
Analytical Composition & Purity Standards
- Chemical Formula: C101H152N28O22S2
- Physical State: White Lyophilized Solid
Our MOTS-c undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≧ 99%.
Investigational Pathways
Researchers utilizing MOTS-c typically focus on the following biochemical mechanisms:
- AMPK Activation: Evaluating the compound’s role in phosphorylating AMP-activated protein kinase to drive cellular energy expenditure.
- Glucose Metabolism: Observing the upregulation of glucose clearance and transport in isolated skeletal muscle models independently of insulin.
- Mitochondrial Retrograde Signaling: Mapping the flux of communication from the mitochondria to the nuclear genome under metabolic stress.
- Folate Cycle Modulation: Investigating the agent’s capacity to inhibit the folate cycle, triggering purine synthesis pathways related to metabolic regulation.
Laboratory Handling & Stability Protocol
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of MOTS-c, the following storage parameters are recommended:
- Thermal Regulation: Store in a strictly controlled, refrigerated, and desiccated environment.
- Photostability: Protect from direct UV exposure; storage in an opaque container is advised.
- Contamination Control: Utilize sterilized instruments and work within a laminar flow hood where possible.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
Frequently asked questions
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A seemingly elegant design can quickly begin to bloat with unexpected content or break under the weight of actual activity. Fake data can ensure a nice looking layout but it doesn’t reflect what a living, breathing application must endure. Real data does.
Websites in professional use templating systems. Commercial publishing platforms and content management systems ensure that you can show different text, different data using the same template. When it’s about controlling hundreds of articles, product pages for web shops.
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