GLP-2 TZ 15mg

$168.00

* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.

Key Specifications

Parameter Specification / Details
Primary Compound Name Retatrutide (Triple-Agonist Peptide)
CAS Registry Number 2381089-83-2
IUPAC Designation (Sequence incorporates Aib, α-MeL, and a C20 fatty diacid moiety at position 17)
Synonyms / Trade Names GLP-3 RE, LY-3437943, Triple-G Agonist
PubChem CID 171390338
Molecular Formula C221​H342​N46​O68​
Molar Mass / Weight 4731.33 g/mol
Physical Appearance White lyophilized (freeze-dried) solid/powder
Solubility Profile Highly soluble in Bacteriostatic Water.
Tested Purity ≥98% via HPLC
Active Ingredient (Total) Typically 2mg, 5mg, or 10mg per vial
Dry / Powder Formulations Lyophilized powder
Alternative Formulations Semaglutide (GLP-1), Tirzepatide (GLP-1/GIP)
Storage Guidelines Lyophilized: Store at -20°C for long-term stability. Protect from light.Reconstituted: Must be refrigerated at 2°C to 8°C.
Estimated Shelf Life 24 months from manufacture date (lyophilized).
Safety Documentation Standard SDS available for Retatrutide
Terms of Application For laboratory research purposes only. Not for human or veterinary use. Investigated as a highly potent tri-agonist to study the synergistic metabolic regulation of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R) in in-vitro energy expenditure and lipid metabolism models.

Foundational Scientific Overview

GLP-3 RE (10mg) represents the cutting edge of multi-target metabolic research. Synthesized as a tri-agonist, it concurrently activates the GLP-1, GIP, and Glucagon (GCG) receptors. It serves researchers examining complex hepatic lipid clearance, maximal energy expenditure, and systemic metabolic reprogramming in pre-clinical models.

At 4 Amino Labs, we provide this highly complex peptide to ensure experimental reproducibility across varied multi-receptor assays.

Scientific Literature Reference: The development of tri-agonists that incorporate glucagon receptor activation to drastically increase energy expenditure while utilizing GLP-1/GIP for glycemic control is highly established in recent molecular literature. See: Tschöp, M. H., et al. (2016). “Unimolecular Polypharmacy for Treatment of Diabetes and Obesity.” Cell Metabolism, 24(1), 51-62.

Analytical Composition & Purity Standards

  • Chemical Formula: Proprietary Tri-Agonist Peptide Sequence
  • Physical State: White Lyophilized Solid

Our GLP-3 RE undergoes a multifaceted verification process via independent High-Performance Liquid Chromatography (HPLC) to verify the precise structural integrity of the complex chain, ensuring a purity threshold of ≥ 99%.

 

Investigational Pathways

Researchers utilizing GLP-3 RE typically focus on the following biochemical mechanisms:

  • Tri-Receptor Kinetics: Evaluating the compound’s simultaneous binding and activation thresholds across hepatic and pancreatic cell lines.
  • Hepatic Steatosis Reversal: Observing the profound reduction of lipid accumulation in isolated hepatocyte models via GCG activation.
  • Maximal Thermogenesis: Mapping the flux of uncoupling proteins (UCPs) and cellular energy output.

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